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Eric Gulve Announces Retirement as President of BioSTL Startup Arm BioGenerator; Charlie Bolten to Take the Helm

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Press release content from PR Newswire. The AP news staff was not involved in its creation.
December 21, 2022 GMT
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Eric Gulve
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Eric Gulve

ST. LOUIS, Dec. 21, 2022 /PRNewswire/ -- Dr. Eric Gulve has announced his retirement from BioSTL after 15 years as President of its startup arm, BioGenerator, and as Executive Vice President of BioSTL. Following a career in academia and the pharmaceutical industry, Gulve became President of BioGenerator in 2009, significantly expanding the number of life science startup companies in St. Louis. Gulve will step down from his post at BioGenerator, effective January 1, 2023, but continue in his role as Executive Vice President of BioSTL, leading many St. Louis ecosystem-building efforts until his retirement mid-2023. Charlie Bolten, Senior Managing Director of BioGenerator, will succeed Gulve as President of BioGenerator.

“Under Eric’s leadership, BioGenerator has fueled the success of locally grown startups to become a nationally respected and celebrated investor and company-builder,” said John McDonnell, BioSTL Board Chair. “Charlie joined the organization shortly after Eric became president, and together, they have established BioGenerator as a nationally renowned innovation hub.”

“Working on behalf of the St. Louis bioscience entrepreneurial community has been the greatest privilege of my career,” said Gulve. “I am extremely grateful to BioSTL’s founders John McDonnell, the late Bill Danforth, and Donn Rubin for their visionary leadership and support of BioGenerator and its mission. I know that under Charlie’s leadership, the organization will continue to grow, thrive and make an even greater impact on the St. Louis startup community and the region’s economy.”

In recent years, Bolten assumed leadership of the BioGenerator Ventures investment portfolio. In addition to investments, Bolten conceptualized and oversees the BioGenerator Labs and manages BioGenerator’s Executives in Residence, both of which were implemented to drive the success of the BioGenerator portfolio.

“Attract great diverse talent, give them the freedom to create, be there to both teach and learn, and hold them accountable – this is Charlie Bolten’s approach to create an exceptional pipeline of both talent and investments,” said Martha Schlicher, PhD, Impetus Ag CEO, Plastomics Board Chair, Solis Agrosciences Board Member, and BioGenerator Executive in Residence. “He attracts and trains new analysts to become entrepreneurs, he attracts first-time entrepreneurs to start companies, and he attracts big-company senior executives to build the BioGenerator portfolio. His fingerprints are everywhere and nowhere in that he often works behind the scenes to ensure the success of both people and companies. You couldn’t ask for a better co-pilot as the CEO of any startup.”

In addition to earning the respect of company CEOs like Schlicher, Bolten’s leadership has attracted many co-investors into the BioGenerator portfolio, which, since its inception, has invested $39 million into more than 100 St. Louis bioscience companies that have collectively raised more than $2.6 billion in follow-on capital, with 85 percent of that funding coming from outside the St. Louis region.

“My respect for Charlie and his commitment to excellence in building and investing in companies led to multiple co-investments between RiverVest and BioGenerator,” said John McKearn, PhD, Managing Director, RiverVest Venture Partners. “Charlie is a valuable asset in every deal, and BioGenerator is very fortunate to have him in this new role.”

“I’ve had the pleasure of working with Charlie Bolten for the last decade, and I can’t think of anyone more capable to take over leadership of BioGenerator,” said Rick Holton Jr., Chief Operating Officer, Hermann Companies. “Hermann Companies looks forward to our committed partnership for the next decade.”

BioGenerator has been behind success stories that include Confluence Life Sciences (acquired by Aclaris; Nasdaq: ACRS), Benson Hill Biosystems (NYSE: BHIL), Canopy Biosciences (acquired by Bruker; Nasdaq: BRKR), and CoverCress (acquired by Bayer AG). BioSTL and those affiliated with the BioGenerator portfolio are confident in Bolten’s ability to continue to deliver successful companies.

“I’ve worked alongside Charlie with a number of companies over the years,” said Bill Schmidt, Managing Director, Life Sciences & Healthcare Innovation Funds, Cultivation Capital. “His attention to detail is unparalleled, and his vision, intellect and leadership make him the ideal candidate to lead BioGenerator in its next phase.”

Bolten, who joined the organization in 2009, will succeed Gulve as President on January 1, 2023.

“When my phone rang in 2009 with an offer to join this organization, I was thrilled,” said Bolten. I had deep respect for Eric’s leadership while at Pfizer and welcomed the opportunity to work with him again. Over the last decade, Eric has encouraged me to experiment and grow into where I am today. His trust and respect were foundational to my success, and I look forward to building upon the strength of the BioGenerator Ventures portfolio.”

Read Eric Gulve’s full biography here. Read Charlie Bolten’s biography here.

About BioSTL

Since 2001, St. Louis nonprofit BioSTL has laid the foundation for the region’s innovation economy with a comprehensive set of transformational programs that advance St. Louis’ leadership in solving important world challenges in agriculture, medicine, healthcare, and other fields. BioSTL has introduced nationally acclaimed initiatives in startup creation and investment (BioGenerator), strategic business attraction (GlobalSTL), physical environment (including the Cortex Innovation District and BioGenerator Labs), entrepreneur support, seed and venture capital, a diverse and inclusive workforce, and public policy. Find us online at and follow us on twitter @BioSTL.

About BioGenerator

BioGenerator, the startup arm of BioSTL, creates and grows innovative St. Louis companies through its two complementary approaches — investing through BioGenerator Ventures and comprehensive startup support through BioGenerator Labs. Visit for additional information, and follow us on LinkedIn at and Twitter @BioGeneratorSTL.

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